diff --git a/cont.c b/cont.c
index 929bbd06c1..072ae4562f 100644
--- a/cont.c
+++ b/cont.c
@@ -551,6 +551,9 @@ fiber_pool_expand(struct fiber_pool * fiber_pool, size_t count)
             VirtualFree(allocation->base, 0, MEM_RELEASE);
             rb_raise(rb_eFiberError, "can't set a guard page: %s", ERRNOMSG);
         }
+#elif defined(__wasi__)
+        // wasi-libc's mprotect emulation doesn't support PROT_NONE.
+        (void)page;
 #else
         if (mprotect(page, RB_PAGE_SIZE, PROT_NONE) < 0) {
             munmap(allocation->base, count*stride);
diff --git a/gc/default/default.c b/gc/default/default.c
index 7e0049bb4f..4cf39a0331 100644
--- a/gc/default/default.c
+++ b/gc/default/default.c
@@ -3199,6 +3199,10 @@ protect_page_body(struct heap_page_body *body, DWORD protect)
     DWORD old_protect;
     return VirtualProtect(body, HEAP_PAGE_SIZE, protect, &old_protect) != 0;
 }
+#elif defined(__wasi__)
+// wasi-libc's mprotect emulation does not support PROT_NONE
+enum {HEAP_PAGE_LOCK, HEAP_PAGE_UNLOCK};
+#define protect_page_body(body, protect) 1
 #else
 enum {HEAP_PAGE_LOCK = PROT_NONE, HEAP_PAGE_UNLOCK = PROT_READ | PROT_WRITE};
 #define protect_page_body(body, protect) !mprotect((body), HEAP_PAGE_SIZE, (protect))
diff --git a/wasm/missing.c b/wasm/missing.c
index 5bbf988642..b9ecf520fd 100644
--- a/wasm/missing.c
+++ b/wasm/missing.c
@@ -119,13 +119,6 @@ umask(rb_mode_t mask)
     return 0;
 }
 
-WASM_MISSING_LIBC_FUNC
-int
-mprotect(const void *addr, size_t len, int prot)
-{
-    return 0;
-}
-
 WASM_MISSING_LIBC_FUNC
 int
 pclose(FILE *stream)