diff --git a/NEWS.md b/NEWS.md
index ac9f282714..3896d23fe5 100644
--- a/NEWS.md
+++ b/NEWS.md
@@ -57,6 +57,11 @@ Note: We're only listing outstanding class updates.
       associated with the AST node. [[Feature #20624]]
     * Add RubyVM::AbstractSyntaxTree::Location class which holds location information. [[Feature #20624]]
 
+* Fiber::Scheduler
+
+    * An optional `Fiber::Scheduler#blocking_region` hook allows blocking operations to be moved out of the event loop
+      in order to reduce latency and improve multi-core processor utilization. [[Feature #20855]]
+
 ## Stdlib updates
 
 * Tempfile
@@ -212,3 +217,4 @@ details of the default gems or bundled gems.
 [Feature #20497]: https://bugs.ruby-lang.org/issues/20497
 [Feature #20624]: https://bugs.ruby-lang.org/issues/20624
 [Feature #20775]: https://bugs.ruby-lang.org/issues/20775
+[Feature #20855]: https://bugs.ruby-lang.org/issues/20855
diff --git a/common.mk b/common.mk
index 4c48f1ebd0..28bb2b7d60 100644
--- a/common.mk
+++ b/common.mk
@@ -16648,6 +16648,7 @@ scheduler.$(OBJEXT): {$(VPATH)}scheduler.c
 scheduler.$(OBJEXT): {$(VPATH)}shape.h
 scheduler.$(OBJEXT): {$(VPATH)}st.h
 scheduler.$(OBJEXT): {$(VPATH)}subst.h
+scheduler.$(OBJEXT): {$(VPATH)}thread.h
 scheduler.$(OBJEXT): {$(VPATH)}thread_$(THREAD_MODEL).h
 scheduler.$(OBJEXT): {$(VPATH)}thread_native.h
 scheduler.$(OBJEXT): {$(VPATH)}vm_core.h
diff --git a/include/ruby/fiber/scheduler.h b/include/ruby/fiber/scheduler.h
index 8f3d383330..bb18b5e01b 100644
--- a/include/ruby/fiber/scheduler.h
+++ b/include/ruby/fiber/scheduler.h
@@ -391,6 +391,26 @@ VALUE rb_fiber_scheduler_io_close(VALUE scheduler, VALUE io);
  */
 VALUE rb_fiber_scheduler_address_resolve(VALUE scheduler, VALUE hostname);
 
+struct rb_fiber_scheduler_blocking_region_state {
+    void *result;
+    int saved_errno;
+};
+
+/**
+ * Defer the execution of the passed function to the scheduler.
+ *
+ * @param[in]  scheduler         Target scheduler.
+ * @param[in]  function          The function to run.
+ * @param[in]  data              The data to pass to the function.
+ * @param[in]  unblock_function  The unblock function to use to interrupt the operation.
+ * @param[in]  data2             The data to pass to the unblock function.
+ * @param[in]  flags             Flags passed to `rb_nogvl`.
+ * @param[out] state             The result and errno of the operation.
+ * @retval     RUBY_Qundef       `scheduler` doesn't have `#blocking_region`.
+ * @return     otherwise         What `scheduler.blocking_region` returns.
+ */
+VALUE rb_fiber_scheduler_blocking_region(VALUE scheduler, void* (*function)(void *), void *data, rb_unblock_function_t *unblock_function, void *data2, int flags, struct rb_fiber_scheduler_blocking_region_state *state);
+
 /**
  * Create and schedule a non-blocking fiber.
  *
diff --git a/scheduler.c b/scheduler.c
index 3159635dba..0d51a0d951 100644
--- a/scheduler.c
+++ b/scheduler.c
@@ -13,6 +13,9 @@
 #include "ruby/io.h"
 #include "ruby/io/buffer.h"
 
+#include "ruby/thread.h"
+
+// For `ruby_thread_has_gvl_p`.
 #include "internal/thread.h"
 
 static ID id_close;
@@ -33,6 +36,8 @@ static ID id_io_close;
 
 static ID id_address_resolve;
 
+static ID id_blocking_region;
+
 static ID id_fiber_schedule;
 
 /*
@@ -109,6 +114,8 @@ Init_Fiber_Scheduler(void)
 
     id_address_resolve = rb_intern_const("address_resolve");
 
+    id_blocking_region = rb_intern_const("blocking_region");
+
     id_fiber_schedule = rb_intern_const("fiber");
 
 #if 0 /* for RDoc */
@@ -693,6 +700,62 @@ rb_fiber_scheduler_address_resolve(VALUE scheduler, VALUE hostname)
     return rb_check_funcall(scheduler, id_address_resolve, 1, arguments);
 }
 
+struct rb_blocking_region_arguments {
+    void *(*function)(void *);
+    void *data;
+    rb_unblock_function_t *unblock_function;
+    void *data2;
+    int flags;
+
+    struct rb_fiber_scheduler_blocking_region_state *state;
+};
+
+static VALUE
+rb_fiber_scheduler_blocking_region_proc(RB_BLOCK_CALL_FUNC_ARGLIST(value, _arguments))
+{
+    struct rb_blocking_region_arguments *arguments = (struct rb_blocking_region_arguments*)_arguments;
+
+    if (arguments->state == NULL) {
+        rb_raise(rb_eRuntimeError, "Blocking function was already invoked!");
+    }
+
+    arguments->state->result = rb_nogvl(arguments->function, arguments->data, arguments->unblock_function, arguments->data2, arguments->flags);
+    arguments->state->saved_errno = rb_errno();
+
+    // Make sure it's only invoked once.
+    arguments->state = NULL;
+
+    return Qnil;
+}
+
+/*
+ *  Document-method: Fiber::Scheduler#blocking_region
+ *  call-seq: blocking_region(work)
+ *
+ *  Invoked by Ruby's core methods to run a blocking operation in a non-blocking way.
+ *
+ *  Minimal suggested implementation is:
+ *
+ *     def blocking_region(work)
+ *       Thread.new(&work).join
+ *     end
+ */
+VALUE rb_fiber_scheduler_blocking_region(VALUE scheduler, void* (*function)(void *), void *data, rb_unblock_function_t *unblock_function, void *data2, int flags, struct rb_fiber_scheduler_blocking_region_state *state)
+{
+    struct rb_blocking_region_arguments arguments = {
+        .function = function,
+        .data = data,
+        .unblock_function = unblock_function,
+        .data2 = data2,
+        .flags = flags,
+        .state = state
+    };
+
+    VALUE proc = rb_proc_new(rb_fiber_scheduler_blocking_region_proc, (VALUE)&arguments);
+
+    return rb_check_funcall(scheduler, id_blocking_region, 1, &proc);
+}
+
 /*
  *  Document-method: Fiber::Scheduler#fiber
  *  call-seq: fiber(&block)
diff --git a/test/fiber/scheduler.rb b/test/fiber/scheduler.rb
index 3926226ca3..91fba0476e 100644
--- a/test/fiber/scheduler.rb
+++ b/test/fiber/scheduler.rb
@@ -309,6 +309,10 @@ class Scheduler
       Addrinfo.getaddrinfo(hostname, nil).map(&:ip_address).uniq
     end.value
   end
+
+  def blocking_region(work)
+    Thread.new(&work).join
+  end
 end
 
 # This scheduler class implements `io_read` and `io_write` hooks which require
@@ -321,8 +325,7 @@ class IOBufferScheduler < Scheduler
     io.nonblock = true
 
     while true
-      maximum_size = buffer.size - offset
-      result = blocking{buffer.read(io, maximum_size, offset)}
+      result = blocking{buffer.read(io, 0, offset)}
 
       if result > 0
         total += result
@@ -349,8 +352,7 @@ class IOBufferScheduler < Scheduler
     io.nonblock = true
 
     while true
-      maximum_size = buffer.size - offset
-      result = blocking{buffer.write(io, maximum_size, offset)}
+      result = blocking{buffer.write(io, 0, offset)}
 
       if result > 0
         total += result
@@ -377,8 +379,7 @@ class IOBufferScheduler < Scheduler
     io.nonblock = true
 
     while true
-      maximum_size = buffer.size - offset
-      result = blocking{buffer.pread(io, from, maximum_size, offset)}
+      result = blocking{buffer.pread(io, from, 0, offset)}
 
       if result > 0
         total += result
@@ -406,8 +407,7 @@ class IOBufferScheduler < Scheduler
     io.nonblock = true
 
     while true
-      maximum_size = buffer.size - offset
-      result = blocking{buffer.pwrite(io, from, maximum_size, offset)}
+      result = blocking{buffer.pwrite(io, from, 0, offset)}
 
       if result > 0
         total += result
diff --git a/test/fiber/test_io.rb b/test/fiber/test_io.rb
index 4891c607f7..39e32c5987 100644
--- a/test/fiber/test_io.rb
+++ b/test/fiber/test_io.rb
@@ -153,12 +153,13 @@ class TestFiberIO < Test::Unit::TestCase
       Fiber.set_scheduler scheduler
 
       Fiber.schedule do
-        message = i.read(20)
+        # We add 1 here, to force the read to block (testing that specific code path).
+        message = i.read(MESSAGE.bytesize + 1)
         i.close
       end
 
       Fiber.schedule do
-        o.write("Hello World")
+        o.write(MESSAGE)
         o.close
       end
     end
diff --git a/test/fiber/test_io_buffer.rb b/test/fiber/test_io_buffer.rb
index a08b1ce1a9..19e6c1f88e 100644
--- a/test/fiber/test_io_buffer.rb
+++ b/test/fiber/test_io_buffer.rb
@@ -21,7 +21,8 @@ class TestFiberIOBuffer < Test::Unit::TestCase
       Fiber.set_scheduler scheduler
 
       Fiber.schedule do
-        message = i.read(20)
+        # We add 1 here, to force the read to block (testing that specific code path).
+        message = i.read(MESSAGE.bytesize + 1)
         i.close
       end
 
diff --git a/test/fiber/test_process.rb b/test/fiber/test_process.rb
index a09b070c0a..f17f767704 100644
--- a/test/fiber/test_process.rb
+++ b/test/fiber/test_process.rb
@@ -59,12 +59,14 @@ class TestFiberProcess < Test::Unit::TestCase
 
   def test_fork
     omit 'fork not supported' unless Process.respond_to?(:fork)
+
+    pid = Process.fork{}
+
     Thread.new do
       scheduler = Scheduler.new
       Fiber.set_scheduler scheduler
 
       Fiber.schedule do
-        pid = Process.fork {}
         Process.wait(pid)
 
         assert_predicate $?, :success?
diff --git a/thread.c b/thread.c
index 2a937ca278..91278e718d 100644
--- a/thread.c
+++ b/thread.c
@@ -1523,6 +1523,18 @@ rb_nogvl(void *(*func)(void *), void *data1,
          rb_unblock_function_t *ubf, void *data2,
          int flags)
 {
+    VALUE scheduler = rb_fiber_scheduler_current();
+    if (scheduler != Qnil) {
+        struct rb_fiber_scheduler_blocking_region_state state;
+
+        VALUE result = rb_fiber_scheduler_blocking_region(scheduler, func, data1, ubf, data2, flags, &state);
+
+        if (!UNDEF_P(result)) {
+            rb_errno_set(state.saved_errno);
+            return state.result;
+        }
+    }
+
     void *val = 0;
     rb_execution_context_t *ec = GET_EC();
     rb_thread_t *th = rb_ec_thread_ptr(ec);