diff --git a/lib/ruby_vm/rjit/insn_compiler.rb b/lib/ruby_vm/rjit/insn_compiler.rb
index 347319dd35..47e842e00e 100644
--- a/lib/ruby_vm/rjit/insn_compiler.rb
+++ b/lib/ruby_vm/rjit/insn_compiler.rb
@@ -18,7 +18,7 @@ module RubyVM::RJIT
       asm.incr_counter(:rjit_insns_count)
       asm.comment("Insn: #{insn.name}")
 
-      # 82/102
+      # 83/102
       case insn.name
       when :nop then nop(jit, ctx, asm)
       when :getlocal then getlocal(jit, ctx, asm)
@@ -31,7 +31,7 @@ module RubyVM::RJIT
       when :getinstancevariable then getinstancevariable(jit, ctx, asm)
       when :setinstancevariable then setinstancevariable(jit, ctx, asm)
       when :getclassvariable then getclassvariable(jit, ctx, asm)
-      # setclassvariable
+      when :setclassvariable then setclassvariable(jit, ctx, asm)
       when :opt_getconstant_path then opt_getconstant_path(jit, ctx, asm)
       when :getconstant then getconstant(jit, ctx, asm)
       # setconstant
@@ -556,7 +556,22 @@ module RubyVM::RJIT
       KeepCompiling
     end
 
-    # setclassvariable
+    # @param jit [RubyVM::RJIT::JITState]
+    # @param ctx [RubyVM::RJIT::Context]
+    # @param asm [RubyVM::RJIT::Assembler]
+    def setclassvariable(jit, ctx, asm)
+      # rb_vm_setclassvariable can raise exceptions.
+      jit_prepare_routine_call(jit, ctx, asm)
+
+      asm.mov(C_ARGS[0], [CFP, C.rb_control_frame_t.offsetof(:iseq)])
+      asm.mov(C_ARGS[1], CFP)
+      asm.mov(C_ARGS[2], jit.operand(0))
+      asm.mov(C_ARGS[3], ctx.stack_pop(1))
+      asm.mov(C_ARGS[4], jit.operand(1))
+      asm.call(C.rb_vm_setclassvariable)
+
+      KeepCompiling
+    end
 
     # @param jit [RubyVM::RJIT::JITState]
     # @param ctx [RubyVM::RJIT::Context]
@@ -1251,6 +1266,9 @@ module RubyVM::RJIT
 
     # checkmatch
 
+    # @param jit [RubyVM::RJIT::JITState]
+    # @param ctx [RubyVM::RJIT::Context]
+    # @param asm [RubyVM::RJIT::Assembler]
     def checkkeyword(jit, ctx, asm)
       # When a keyword is unspecified past index 32, a hash will be used
       # instead. This can only happen in iseqs taking more than 32 keywords.
diff --git a/rjit_c.c b/rjit_c.c
index 3d4d22742e..1a2aa0b1b1 100644
--- a/rjit_c.c
+++ b/rjit_c.c
@@ -496,6 +496,7 @@ extern rb_event_flag_t rb_rjit_global_events;
 extern void rb_vm_setinstancevariable(const rb_iseq_t *iseq, VALUE obj, ID id, VALUE val, IVC ic);
 extern VALUE rb_vm_throw(const rb_execution_context_t *ec, rb_control_frame_t *reg_cfp, rb_num_t throw_state, VALUE throwobj);
 extern VALUE rb_reg_new_ary(VALUE ary, int opt);
+extern void rb_vm_setclassvariable(const rb_iseq_t *iseq, const rb_control_frame_t *cfp, ID id, VALUE val, ICVARC ic);
 
 #include "rjit_c.rbinc"
 
diff --git a/rjit_c.rb b/rjit_c.rb
index a582fd80ba..17aa6754f0 100644
--- a/rjit_c.rb
+++ b/rjit_c.rb
@@ -625,6 +625,10 @@ module RubyVM::RJIT # :nodoc: all
     Primitive.cexpr! %q{ SIZET2NUM((size_t)rb_vm_opt_newarray_min) }
   end
 
+  def C.rb_vm_setclassvariable
+    Primitive.cexpr! %q{ SIZET2NUM((size_t)rb_vm_setclassvariable) }
+  end
+
   def C.rb_vm_setinstancevariable
     Primitive.cexpr! %q{ SIZET2NUM((size_t)rb_vm_setinstancevariable) }
   end
diff --git a/tool/rjit/bindgen.rb b/tool/rjit/bindgen.rb
index 9c1cbdfcc9..2e472a411b 100755
--- a/tool/rjit/bindgen.rb
+++ b/tool/rjit/bindgen.rb
@@ -542,6 +542,7 @@ generator = BindingGenerator.new(
     rb_reg_new_ary
     rb_ary_clear
     rb_str_intern
+    rb_vm_setclassvariable
   ],
   types: %w[
     CALL_DATA