diff --git a/src/corelib/Qt5CoreConfigExtras.cmake.in b/src/corelib/Qt5CoreConfigExtras.cmake.in
index a80427893df..e01b4483512 100644
--- a/src/corelib/Qt5CoreConfigExtras.cmake.in
+++ b/src/corelib/Qt5CoreConfigExtras.cmake.in
@@ -83,6 +83,8 @@ list(APPEND Qt5Core_COMPILE_DEFINITIONS QT_NAMESPACE=$$QT_NAMESPACE)
 set_property(TARGET Qt5::Core APPEND PROPERTY INTERFACE_COMPILE_DEFINITIONS QT_NAMESPACE=$$QT_NAMESPACE)
 !!ENDIF
 
+set_property(TARGET Qt5::Core APPEND PROPERTY INTERFACE_COMPILE_DEFINITIONS $<$<NOT:$<CONFIG:Debug>>:QT_NO_DEBUG>)
+
 !!IF contains(QT_CONFIG, reduce_exports)
 set(QT_VISIBILITY_AVAILABLE \"True\")
 !!ENDIF