diff --git a/src/corelib/Qt6CoreDeploySupport.cmake b/src/corelib/Qt6CoreDeploySupport.cmake
index e189b265387..6560a23e1b4 100644
--- a/src/corelib/Qt6CoreDeploySupport.cmake
+++ b/src/corelib/Qt6CoreDeploySupport.cmake
@@ -404,6 +404,13 @@ function(qt6_deploy_runtime_dependencies)
         if(arg_NO_COMPILER_RUNTIME)
             list(APPEND tool_options --no-compiler-runtime)
         endif()
+
+        # Specify path to target Qt's qtpaths .exe or .bat file, so windeployqt deploys the correct
+        # libraries when cross-compiling from x86_64 to arm64 windows.
+        if(__QT_DEPLOY_TARGET_QT_PATHS_PATH)
+            list(APPEND tool_options --qtpaths "${__QT_DEPLOY_TARGET_QT_PATHS_PATH}")
+        endif()
+
         list(APPEND tool_options ${arg_DEPLOY_TOOL_OPTIONS})
     elseif(__QT_DEPLOY_SYSTEM_NAME STREQUAL Darwin)
         set(extra_binaries_option "-executable=")
diff --git a/src/corelib/Qt6CoreMacros.cmake b/src/corelib/Qt6CoreMacros.cmake
index e80bf0bbacb..c4e7e815641 100644
--- a/src/corelib/Qt6CoreMacros.cmake
+++ b/src/corelib/Qt6CoreMacros.cmake
@@ -2863,6 +2863,20 @@ function(_qt_internal_setup_deploy_support)
         endif()
     endif()
 
+    # Generate path to the target (not host) qtpaths file. Needed for windeployqt when
+    # cross-compiling from an x86_64 host to an arm64 target, so it knows which architecture
+    # libraries should be deployed.
+    if(CMAKE_HOST_WIN32)
+        if(CMAKE_CROSSCOMPILING)
+            set(qt_paths_ext ".bat")
+        else()
+            set(qt_paths_ext ".exe")
+        endif()
+    else()
+        set(qt_paths_ext "")
+    endif()
+    set(target_qtpaths_path "${QT6_INSTALL_PREFIX}/${QT6_INSTALL_BINS}/qtpaths${qt_paths_ext}")
+
     file(GENERATE OUTPUT "${QT_DEPLOY_SUPPORT}" CONTENT
 "cmake_minimum_required(VERSION 3.16...3.21)
 
@@ -2909,6 +2923,7 @@ set(__QT_DEPLOY_QT_INSTALL_PREFIX \"${QT6_INSTALL_PREFIX}\")
 set(__QT_DEPLOY_QT_INSTALL_BINS \"${QT6_INSTALL_BINS}\")
 set(__QT_DEPLOY_QT_INSTALL_PLUGINS \"${QT6_INSTALL_PLUGINS}\")
 set(__QT_DEPLOY_QT_INSTALL_TRANSLATIONS \"${QT6_INSTALL_TRANSLATIONS}\")
+set(__QT_DEPLOY_TARGET_QT_PATHS_PATH \"${target_qtpaths_path}\")
 set(__QT_DEPLOY_PLUGINS \"\")
 set(__QT_DEPLOY_MUST_ADJUST_PLUGINS_RPATH \"${must_adjust_plugins_rpath}\")
 set(__QT_DEPLOY_USE_PATCHELF \"${QT_DEPLOY_USE_PATCHELF}\")