diff --git a/mysql-test/r/delete.result b/mysql-test/r/delete.result
index 77b2071494d..36025cbfb35 100644
--- a/mysql-test/r/delete.result
+++ b/mysql-test/r/delete.result
@@ -349,4 +349,13 @@ END |
 DELETE IGNORE FROM t1;
 ERROR HY000: Can't update table 't1' in stored function/trigger because it is already used by statement which invoked this stored function/trigger.
 DROP TABLE t1;
+#
+# Bug #53450: Crash/assertion
+#    "virtual int ha_myisam::index_first(uchar*)") at assert.c:81
+#
+CREATE TABLE t1 (a INT,    b INT,    c INT,
+INDEX(a), INDEX(b), INDEX(c));
+INSERT INTO t1 VALUES (1,2,3), (4,5,6), (7,8,9);
+DELETE FROM t1 WHERE a = 10 OR b = 20 ORDER BY c LIMIT 1;
+DROP TABLE t1;
 End of 5.1 tests
diff --git a/mysql-test/t/delete.test b/mysql-test/t/delete.test
index 7bbc470137a..5a0e86568f3 100644
--- a/mysql-test/t/delete.test
+++ b/mysql-test/t/delete.test
@@ -374,5 +374,17 @@ DELETE IGNORE FROM t1;
 
 DROP TABLE t1;
 
+--echo #
+--echo # Bug #53450: Crash/assertion
+--echo #    "virtual int ha_myisam::index_first(uchar*)") at assert.c:81
+--echo #
+
+CREATE TABLE t1 (a INT,    b INT,    c INT,
+                 INDEX(a), INDEX(b), INDEX(c));
+INSERT INTO t1 VALUES (1,2,3), (4,5,6), (7,8,9);
+
+DELETE FROM t1 WHERE a = 10 OR b = 20 ORDER BY c LIMIT 1;
+
+DROP TABLE t1;
 
 --echo End of 5.1 tests
diff --git a/sql/sql_delete.cc b/sql/sql_delete.cc
index cc29b6f1b6b..07421ca55a6 100644
--- a/sql/sql_delete.cc
+++ b/sql/sql_delete.cc
@@ -266,7 +266,7 @@ bool mysql_delete(THD *thd, TABLE_LIST *table_list, COND *conds,
     free_underlaid_joins(thd, select_lex);
     DBUG_RETURN(TRUE);
   }
-  if (usable_index==MAX_KEY)
+  if (usable_index==MAX_KEY || (select && select->quick))
     init_read_record(&info, thd, table, select, 1, 1, FALSE);
   else
     init_read_record_idx(&info, thd, table, 1, usable_index);