diff --git a/mysql-test/suite/galera/r/galera_cache_index.result b/mysql-test/suite/galera/r/galera_cache_index.result
new file mode 100644
index 00000000000..d8172e6bd0d
--- /dev/null
+++ b/mysql-test/suite/galera/r/galera_cache_index.result
@@ -0,0 +1,49 @@
+connection node_2;
+connection node_1;
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=innodb;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int);
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CREATE TEMPORARY TABLE t1 (c1 INT) ENGINE=MRG_MyISAM UNION=(t1,t2) INSERT_METHOD=LAST;
+CACHE INDEX t1,t2 IN default;
+Table	Op	Msg_type	Msg_text
+test.t1	assign_to_keycache	Error	Table 't1' is differently defined or of non-MyISAM type or doesn't exist
+test.t1	assign_to_keycache	error	Corrupt
+test.t2	assign_to_keycache	note	The storage engine for the table doesn't support assign_to_keycache
+LOAD INDEX INTO CACHE t1,t2;
+Table	Op	Msg_type	Msg_text
+test.t1	preload_keys	Error	Table 't1' is differently defined or of non-MyISAM type or doesn't exist
+test.t1	preload_keys	error	Corrupt
+test.t2	preload_keys	note	The storage engine for the table doesn't support preload_keys
+DROP TEMPORARY TABLE t1;
+DROP TABLE t1,t2;
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CREATE TEMPORARY TABLE t1 (c1 INT) ENGINE=MRG_MyISAM UNION=(t1,t2) INSERT_METHOD=LAST;
+CACHE INDEX t1,t2 IN default;
+Table	Op	Msg_type	Msg_text
+test.t1	assign_to_keycache	Error	Table 't1' is differently defined or of non-MyISAM type or doesn't exist
+test.t1	assign_to_keycache	error	Corrupt
+test.t2	assign_to_keycache	status	OK
+LOAD INDEX INTO CACHE t1,t2;
+Table	Op	Msg_type	Msg_text
+test.t1	preload_keys	Error	Table 't1' is differently defined or of non-MyISAM type or doesn't exist
+test.t1	preload_keys	error	Corrupt
+test.t2	preload_keys	status	OK
+DROP TEMPORARY TABLE t1;
+DROP TABLE t1,t2;
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CACHE INDEX t1,t2 IN default;
+Table	Op	Msg_type	Msg_text
+test.t1	assign_to_keycache	status	OK
+test.t2	assign_to_keycache	status	OK
+LOAD INDEX INTO CACHE t1,t2;
+Table	Op	Msg_type	Msg_text
+test.t1	preload_keys	status	OK
+test.t2	preload_keys	status	OK
+DROP TABLE t1,t2;
diff --git a/mysql-test/suite/galera/t/galera_cache_index.test b/mysql-test/suite/galera/t/galera_cache_index.test
new file mode 100644
index 00000000000..b373a173894
--- /dev/null
+++ b/mysql-test/suite/galera/t/galera_cache_index.test
@@ -0,0 +1,29 @@
+--source include/galera_cluster.inc
+
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=innodb;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int);
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CREATE TEMPORARY TABLE t1 (c1 INT) ENGINE=MRG_MyISAM UNION=(t1,t2) INSERT_METHOD=LAST;
+CACHE INDEX t1,t2 IN default;
+LOAD INDEX INTO CACHE t1,t2;
+DROP TEMPORARY TABLE t1;
+DROP TABLE t1,t2;
+
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CREATE TEMPORARY TABLE t1 (c1 INT) ENGINE=MRG_MyISAM UNION=(t1,t2) INSERT_METHOD=LAST;
+CACHE INDEX t1,t2 IN default;
+LOAD INDEX INTO CACHE t1,t2;
+DROP TEMPORARY TABLE t1;
+DROP TABLE t1,t2;
+
+CREATE TABLE t1 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t1 VALUES (1),(2),(3),(4),(5);
+CREATE TABLE t2 (c1 int, UNIQUE INDEX (c1)) engine=MyISAM;
+INSERT INTO t2 VALUES (1),(2),(3),(4),(5);
+CACHE INDEX t1,t2 IN default;
+LOAD INDEX INTO CACHE t1,t2;
+DROP TABLE t1,t2;
diff --git a/sql/sql_admin.cc b/sql/sql_admin.cc
index ce472697d40..66dfc93f45d 100644
--- a/sql/sql_admin.cc
+++ b/sql/sql_admin.cc
@@ -33,6 +33,10 @@
 #include "sql_admin.h"
 #include "sql_statistics.h"
 #include "wsrep_mysqld.h"
+#ifdef WITH_WSREP
+#include "wsrep_trans_observer.h"
+#endif
+
 /* Prepare, run and cleanup for mysql_recreate_table() */
 
 static bool admin_recreate_table(THD *thd, TABLE_LIST *table_list,
@@ -437,6 +441,32 @@ dbug_err:
   return open_error;
 }
 
+#ifdef WITH_WSREP
+/** RAII class for temporarily disable wsrep_on in the connection. */
+class Disable_wsrep_on_guard
+{
+ public:
+  /**
+    @param thd     - pointer to the context of connection in which
+                     wsrep_on mode needs to be disabled.
+    @param disable - true if wsrep_on should be disabled
+  */
+  explicit Disable_wsrep_on_guard(THD *thd, bool disable)
+    : m_thd(thd), m_orig_wsrep_on(thd->variables.wsrep_on)
+  {
+    if (disable)
+      thd->variables.wsrep_on= false;
+  }
+
+  ~Disable_wsrep_on_guard()
+  {
+    m_thd->variables.wsrep_on= m_orig_wsrep_on;
+  }
+ private:
+  THD* m_thd;
+  bool m_orig_wsrep_on;
+};
+#endif /* WITH_WSREP */
 
 /*
   RETURN VALUES
@@ -473,6 +503,18 @@ static bool mysql_admin_table(THD* thd, TABLE_LIST* tables,
   DBUG_ENTER("mysql_admin_table");
   DBUG_PRINT("enter", ("extra_open_options: %u", extra_open_options));
 
+#ifdef WITH_WSREP
+  /*
+    CACHE INDEX and LOAD INDEX INTO CACHE statements are
+    local operations. Do not replicate them with Galera
+  */
+  const bool disable_wsrep_on= (WSREP(thd) &&
+    (lex->sql_command == SQLCOM_ASSIGN_TO_KEYCACHE ||
+     lex->sql_command == SQLCOM_PRELOAD_KEYS));
+
+  Disable_wsrep_on_guard wsrep_on_guard(thd, disable_wsrep_on);
+#endif /* WITH_WSREP */
+
   field_list.push_back(item= new (thd->mem_root)
                        Item_empty_string(thd, "Table",
                                          NAME_CHAR_LEN * 2), thd->mem_root);
@@ -535,7 +577,6 @@ static bool mysql_admin_table(THD* thd, TABLE_LIST* tables,
                                 ? MDL_SHARED_NO_READ_WRITE
                                 : lock_type >= TL_WRITE_ALLOW_WRITE
                                 ? MDL_SHARED_WRITE : MDL_SHARED_READ);
-
     if (thd->check_killed())
     {
       open_error= false;
diff --git a/sql/wsrep_trans_observer.h b/sql/wsrep_trans_observer.h
index 4c9346739fe..cf5063df04d 100644
--- a/sql/wsrep_trans_observer.h
+++ b/sql/wsrep_trans_observer.h
@@ -193,6 +193,11 @@ static inline bool wsrep_run_commit_hook(THD* thd, bool all)
                        wsrep_is_active(thd), wsrep_is_real(thd, all),
                        wsrep_has_changes(thd), wsrep_thd_is_applying(thd),
                        wsrep_is_ordered(thd)));
+
+  /* skipping non-wsrep threads */
+  if (!WSREP(thd))
+    DBUG_RETURN(false);
+
   /* Is MST commit or autocommit? */
   bool ret= wsrep_is_active(thd) && wsrep_is_real(thd, all);
   /* Do not commit if we are aborting */