diff --git a/mysql-test/r/handler.result b/mysql-test/r/handler.result
index dc3750e16ea..4906111982f 100644
--- a/mysql-test/r/handler.result
+++ b/mysql-test/r/handler.result
@@ -502,3 +502,7 @@ handler t1_alias READ a next where inexistent > 0;
 ERROR 42S22: Unknown column 'inexistent' in 'field list'
 handler t1_alias close;
 drop table t1;
+USE information_schema;
+HANDLER COLUMNS OPEN;
+ERROR HY000: Incorrect usage of HANDLER OPEN and information_schema
+USE test;
diff --git a/mysql-test/t/handler.test b/mysql-test/t/handler.test
index 6ef216f6ed2..70d4157a272 100644
--- a/mysql-test/t/handler.test
+++ b/mysql-test/t/handler.test
@@ -460,3 +460,11 @@ handler t1_alias read a next;
 handler t1_alias READ a next where inexistent > 0;
 handler t1_alias close;
 drop table t1;
+
+#
+# Bug#44151 using handler commands on information_schema tables crashes server
+#
+USE information_schema;
+--error ER_WRONG_USAGE
+HANDLER COLUMNS OPEN;
+USE test;
diff --git a/sql/sql_handler.cc b/sql/sql_handler.cc
index c376f1b3d1d..721b365a7b9 100644
--- a/sql/sql_handler.cc
+++ b/sql/sql_handler.cc
@@ -190,6 +190,14 @@ bool mysql_ha_open(THD *thd, TABLE_LIST *tables, bool reopen)
                       tables->db, tables->table_name, tables->alias,
                       (int) reopen));
 
+  if (tables->schema_table)
+  {
+    my_error(ER_WRONG_USAGE, MYF(0), "HANDLER OPEN",
+             INFORMATION_SCHEMA_NAME.str);
+    DBUG_PRINT("exit",("ERROR"));
+    DBUG_RETURN(TRUE);
+  }
+
   if (! hash_inited(&thd->handler_tables_hash))
   {
     /*